WORLD DAY FOR LABORATORY ANIMALS

FRIDAY - APRIL 24, 1998
7:30am to 1:00pm
WISEMAN HALL - Ohio State Campus - 410 W. 12th Ave.


The numbers of animals used for experimentation and education at Ohio State University increased by 51% from 1996 to 1997.

POET continues to be very concerned about the animals used in projects where pain and distress are not relieved. Approx. $500,000 (your tax dollars) are being directed toward a series of projects using mice where pain and distress are not relieved. Animals are placed in a stressed environment in hopes of causing Epstein-Barr Virus and/or to better understand mechanisms controlling the immune response to stress. Interesting to note is that much of the same work is already being done using humans. It is time to halt the animal projects and use the money to help people directly.

The number of primates reported at OSU is listed as 52 for 1997. This number will increase in 1998 unless the xenotransplant project of Dr. Robert Michler is halted. In December, ILACUC (Institutional Laboratory Animal Care and Use Committee) approved a Michler project which will use 60 pigs and 120 baboons. While the original protocol called for the animals to be euthanized, POET has since learned that after the xenotransplantion, researchers plan to keep a selected number of baboons alive for at least two years. In a March 1998 press release, Campaign for Responsible Transplantation, made the following statement: “Evidence mounts, on a weekly basis, that we should not be transplanting virally contaminated animal organs into humans. Baboons and pigs are still designated organ donors for xenotransplants, despite warning by prominent virologists that (the animals) harbor several endogenous retroviruses, some that can infect human cells.” There is no way to screen for viruses that are not yet known. Scientists continue to discover new viruses in primates and pigs that were heretofore unknown.

Last fall, the AAVS launched a campaign to stop the production of monoclonal antibodies (MAb ) in animals. There are in vitro (animal-free) alternatives available which produce purer antibodies. The Office of Protection from Research Risks has issued a letter stating that ILACUC’s are expected to critically evaluate the use of the mouse ascites (edema) method. There is evidence that the mouse ascites method of MAb production causes discomfort, distress, or pain. The OSU ILACUC should evaluate projects involving MAb production in mice. It’s time to stop the suffering and pain!

UPDATE: After a complaint was filed with NIH OSU changed their policy concerning MaB. Will include information.